Protein name:
Matrix metalloproteinase-16 (MMP-16) ;
Alternative:
Membrane-type matrix metalloproteinase 3 (MT-MMP 3;MTMMP3) ;MMP-X2 ;Membrane-type-3 matrix metalloproteinase (MT3-MMP;MT3MMP) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with CSPG4 through CSPG4 chondroitin sulfate glycosaminoglycan.
Function:
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Subcellular Location:
Isoform Short
Secreted
extracellular space
extracellular matrix
Cell surface
Localized at the cell surface of melanoma cells.
Protein Attributes:
50:
MILLTFSTGR | RLDFVHHSGV | FFLQTLLWIL | CATVCGTEQY | FNVEVWLQKY |
100:
GYLPPTDPRM | SVLRSAETMQ | SALAAMQQFY | GINMTGKVDR | NTIDWMKKPR |
150:
CGVPDQTRGS | SKFHIRRKRY | ALTGQKWQHK | HITYSIKNVT | PKVGDPETRK |
200:
AIRRAFDVWQ | NVTPLTFEEV | PYSELENGKR | DVDITIIFAS | GFHGDSSPFD |
250:
GEGGFLAHAY | FPGPGIGGDT | HFDSDEPWTL | GNPNHDGNDL | FLVAVHELGH |
300:
ALGLEHSNDP | TAIMAPFYQY | METDNFKLPN | DDLQGIQKIY | GPPDKIPPPT |
350:
RPLPTVPPHR | SIPPADPRKN | DRPKPPRPPT | GRPSYPGAKP | NICDGNFNTL |
400:
AILRREMFVF | KDQWFWRVRN | NRVMDGYPMQ | ITYFWRGLPP | SIDAVYENSD |
450:
GNFVFFKGNK | YWVFKDTTLQ | PGYPHDLITL | GSGIPPHGID | SAIWWEDVGK |
500:
TYFFKGDRYW | RYSEEMKTMD | PGYPKPITVW | KGIPESPQGA | FVHKENGFTY |
550:
FYKGKEYWKF | NNQILKVEPG | YPRSILKDFM | GCDGPTDRVK | EGHSPPDDVD |
600:
IVIKLDNTAS | TVKAIAIVIP | CILALCLLVL | VYTVFQFKRK | GTPRHILYCK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human MMP-16
ELISA Kit for Human MMP-16
ELISA Kit for Human MMP-16
CLIA Kit for Human MMP-16
CLIA Kit for Human MMP-16
CLIA Kit for Human MMP-16
Polyclonal Antibody for Human MMP-16
Polyclonal Antibody for Human MMP-16
Polyclonal Antibody for Human MMP-16
Monoclonal Antibody for Human MMP-16
Monoclonal Antibody for Human MMP-16
Monoclonal Antibody for Human MMP-16
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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